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Dr. Anupam Nath Jha

Research Interest

Computational Biophysics, Structural Bioinformatics, Systems Biology 

https://publons.com/researcher/3624321/anupam-nath-jha/

https://loop.frontiersin.org/people/763265/overview

Position held

1) Assistant Professor (Grade-III) (2020 -- Present) 

2) Assistant Professor (Grade-II) (2015 - 2020) 

3) Assistant Professor (Grade-I) (2011- 2015)

Education qualification

    Ph. D. (Computational Biophysics) in 2010 from Molecular Biophysics Unit (MBU), Indian Institute of Science (IISc), Bangalore

    M. Sc. (Physics) in 2004 from Banaras Hindu University (BHU), Varanasi

    B.Sc. (Physics (Hons)) in 2002 from Banaras Hindu University (BHU), Varanasi


Ongoing projects

Sl. Title Sponsored Start date End date Fund
1 Strategic Systems Biology and Metabolic Pathways approach to develop nanocarriers for targeted drug delivery SERB-DST 2021-03-30 26Lakhs
2 Integrated WGS and metabolic pathway analysis for SNPs related to drug resistance for targeted drug development ICMR 23 Lakhs

Completed projects

SL Title Sponsored Start date End date Fund
1 Search of potent inhibitors against target from L donovani (Visceral Leishmaniasis) using systems biology, virtual screening and molecular dynamics DBT 2019-04-29 15 Lakhs
2 Biophysical Characterization of adenylosuccinate lyase‐ a potential drug target from Leishmania donovani‐ a computational and molecular approach DBT 2017-02-13 2020-08-12 70 Lakhs
3 Nanoparticle based approach to enhance the AMP efficacy against AMP resistant bacteria DBT 2016-10-18 2020-04-17 38 Lakhs
4 In-Silico design and evaluation of sequences for γD crystallin protein DBT 2013-01-04 2016-07-03 50 Lakhs

Publication

  1. Indu Kumari, Dinesh Lakhanpal, Sandeep Swargam and Anupam Nath Jha, Leishmaniasis: Omics approaches to understand its biology from molecule to cell level, Current Protein & Peptide Science, 23: 548 - 562, 2023, 3.118, Click Here (DOI)
  2. Debanjan Saha and Anupam Nath Jha, Computational multi‐target approach to target essential enzymes of Leishmania donovani using comparative molecular dynamic simulations and MMPBSA analysis, Phytochemical Analysis, 23: 548 - 562, 2023, 3.024, Click Here (DOI)
  3. Saynaz A Choudhary, Debarun Patra, Archana Sinha, Sayani Mazumder, Rajat Pant, Raju Chouhan, Anupam Nath Jha, Biswamohan Prusty, Debasis Manna, Sajal K Das, Kulbhushan Tikoo, Durba Pal and Suman Dasgupta, A small molecule potent IRAK4 inhibitor abrogates lipopolysaccharide-induced macrophage inflammation in-vitro and in-vivo, European Journal of Pharmacology, 436: 114425, 2023, 4.96, Click Here (DOI)
  4. Sona Lyndem, Upasana Hazarika, P Athul, Anindita Bhatta, Vivek Prakash, Anupam Nath Jha and Atanu Singha Roy, A comprehensive in vitro exploration into the interaction mechanism of coumarin derivatives with bovine hemoglobin: Spectroscopic and computational methods, Journal of Photochemistry and Photobiology A: Chemistry, 436: 114425 , 2022, 5.141 , Click Here (DOI)
  5. Omkar Indari, Ajit Kumar Singh, Deeksha Tiwari, Hem Chandra Jha and Anupam Nath Jha, Deciphering antiviral efficacy of malaria box compounds against malaria exacerbating viral pathogens-Epstein Barr Virus and SARS-CoV-2, an in silico study, Medicine in Drug Discovery, 16: 100146, 2022, 16: 100146, Click Here (DOI)
More Publication >>

Books

  1. Molecular Dynamics Simulations: A Tool to Investigate the Interactions between Biomolecules and Nanoparticles, An Introduction to Molecular Dynamics, 2019, Nova Science Publishers Inc
  2. Role of Force Fields in Protein Function Prediction, Homology Molecular Modeling, 2020, IntechOpen
  3. Systems biology and bioinformatics approaches in leishmaniasis, Applications of Nanobiotechnology for Neglected Tropical Diseases , 2021, Academic Press
  4. Plasmodium falciparum: Experimental and Theoretical Approaches in Last 20 Years, Current Topics and Emerging Issues in Malaria Elimination , 2021, IntechOpen

Awards

SL Awards Year

Research Scholars

Debanjan Saha
Debanjan Saha Contact: +91-3712-275433 Email: dsaha@tezu.ernet.in

Education: M. Sc. in Life science (Zoology) 2017, Assam University, Silchar  

Year of joining PhD:  July 2019


Project Students


M.Sc. students


Integrated M.Sc. students


Alumni

Neeraj Singh

Neeraj Singh

Contact: NA Email: nil

M.Sc. Project entitled "Amino acid preferences in intrinsically disordered protein" during 2012

Pankaj Losan Sharma

Pankaj Losan Sharma

Contact: NA Email: nil

M.Sc. project entitled “Computational studies of intrinsically disordered region of proteins: SRP19 of Human and Pectate lyase KSM-P15 of Bacillus sp" during 2013

Sapna Mayuri Borah

Sapna Mayuri Borah

Contact: NA Email: nil

M.Sc. project entitled “Structural and Functional Studies of HopS2 effector protein" during 2014

Narendra Kumar

Narendra Kumar

Contact: NA Email: nil

M.Sc. project entitled “In silico studies of Influenza A virus proteins" during 2015

Rahul Pegu

Rahul Pegu

Contact: NA Email: nil

M.Sc. project entitled “Computational identification of drought stress responsive miRNA in rice (Oryza sativa)" during 2016

Rashmirekha Boruah

Rashmirekha Boruah

Contact: NA Email: nil

M.Sc. project entitled “Phylogenetic Analysis of Hrp-dependent outer Proteins" during 2017

Lini Boro

Lini Boro

Contact: NA Email: nil

M.Sc. project entitled “Structural Analysis of Bacterial Exotoxins" during  2017

Activity Details

SL Title Year Type

Dr. Anupam Nath Jha

Assistant Professor

Phone: 5416
Mobile:
TU Email: anjha@tezu.ernet.in
Other email: anjha@tezu.ac.in

Courses Taught

  • Basics of Chemistry and Physics: Course # BT 451.
  • Application of Computer in Biotechnology: Course # BT 414.
  • Biostatistics and Computer Applications: Course # BT 405.
  • Basics in Bio-computing: Course # BI 226.
  • Bioprogramming and Biostatistics: Course # BI 327.
  • Computational Biology: Course # BI 330.
  • Structural Bioinformatics: Course # BI 421.