Course Plan
(Spring Semester)
CBCT
BE522: Basic Neuroengineering (CBCT) 

The integration of biomolecules with electronic elements to yield functional devices attracts substantial research efforts because of the basic fundamental scientific questions and the potential practical applications of the systems. The research field gained the buzzword "bioelectronics" aimed at highlighting that the world of electronics could be cross fertilized with biology and biotechnology. The major activities in the field of bioelectronics relate to the development of biosensors that transduce biorecognition or biocatalytic processes in the form of electronic signals. Neuroengineering, or more precisely Bioneuroengineering which is inseparable part of Bioelectronics, is an interdisciplinary area, with the common goal of analyzing the function of the nervous system, developing methods to restore damaged neurological function & creating artificial neuronal systems by integrating physical, chemical, mathematical & engineering tools. The development of artificial circuit models that simulate the behavior of biological neuron is one of today's most promising directions of investigation in the field of neurobio and neuromorphic engineering. 
Objective visavis Lecture Modules 


Modules 
Topic  Learning Objectives  
1 
Introduction 
Biology of the neuron, Biophysical description of the action potential, Synapses 

2 
Membrane 
Membrane transport, Membrane capacitance 

3 
HodgkinHuxley (HH) Model 
HH model of membrane, Membrane currents, Cable equation. 

4 
Myelinated Nerve 
Electric circuit model of myelinated nerve 

5 
Neural modeling 
Linear dendritic model, Varicosities & impulse conduction, Information processing in dendrites 

6 
Silicon model of neuron 
HH model, synapse model, simple neuron logic gates. 

7 
Neuronal networks 
Neuronal networks, Neural coding 
Prerequisites of the course 

Basic understanding of Biology, Physiology of human body and basic knowledge of electronics is desired but not essential. 
Lecture Plan 


Tentative Lecture  Topics  
1 
Introduction  
23 
Biology of the neuron  
45 
Biophysical description of the action potential  
68 
Synapses: Chemical Synapse, Electrical circuit model of synapse  
9 
Membrane transport  
10 
Membrane capacitance  
11 12 
HodgkinHuxley (HH) Model of membrane  
1314 
Membrane currents  
1516 
Cable equation  
17 
Myelinated Nerve  
1819 
Electric circuit model of myelinated nerve  
2021 
Neural modeling: Linear dendritic model  
2223 
Varicosities & impulse conduction  
2425 
Information processing in dendrites  
2627 
Silicon model of neuron: HH model  
2829 
Synapse model, simple neuron logic gates  
3031 
Neuronal networks  
3233 
Neural coding 
Pedagogy 

Class Room Lectures

Expected outcome 

After completing the course BE 522, student is expected to have the basic knowledge of the Bio neuroengineering and students are expected to work in the field of Bioneuroengineering as project work or as per their interest.

Text/Reference Book 

1. Grattarola, M.
Massobrio, G. Bioelectronics Handbook, MOSFETs, Biosensors & Neurons;
McGraw Hill 4. Metin, A. Neural Engineering; Wiley/IEEE Press,Vol 16 