Snake venom biochemistry, structure-function relation of venom protein.
Post Doctoral Research (2005-2009): National University of Singapore, Singapore
PhD (2005): Department of Molecular Biology and Biotechnology, Tezpur University, Assam, India
Master in Science (1999): Zoology (Honors) , Rajiv Gandhi University (Formerly Arunachal University), Doimukh, Arunachal Pradesh, India
Bachelor’s degree in Science (1997): Zoology (Honors),J.N. College Pasighat, Arunachal Pradesh, India
| Sl. | Title | Sponsored | Start date | End date | Fund |
|---|---|---|---|---|---|
| 1 | Design of aptamers against venom protein of Trimeresurus erythrurus and its validation: An alternative approach for anti-snake venom | DST- EMEQ | 2023-01-05 | Rs. 4484829.00 |
| SL | Title | Sponsored | Start date | End date | Fund |
|---|---|---|---|---|---|
| 1 | Search for novel treatments for snake venom poisoning: Composition analysis of venoms of snake family Naja naja and Daboia russelii and complete characterization of their major toxins. | Department of Biotechnology, Ministry of Science and Technology, Govt. of India | 2011-03-01 | 2014-09-30 | 69.84 Lakhs |
| 2 | Isolation, characterization, possible use and clinical manifestation of a Neurotoxin from Snake venom (Naja siamensis) with special reference to warfare importance neuro- toxin as a model. | DRDO, Govt. of India | 2012-02-01 | 2015-01-31 | 9.8 Lakhs |
| 3 | Cloning, expression and structural characterization of anti-thrombin from cattle tick salivary gland: designing of novel anti-thrombin peptide. | Department of Science and Technology, Govt. of India | 2014-07-01 | 2018-06-30 | 41.06 Lakhs |
| 4 | Co-PI:Biodiversity Informatics and Technology Exchange for Snakebite management (BITES) Partner 5 of MARIE CURIE ACTIONS International Research Staff Exchange Scheme (IRSES) | European Commission | 2014-09-01 | 2018-08-31 | |
| 5 | Aptamer based rapid test to differentiate venomous snake bites from non-venomous and dry snake bites. | BIRAC | 2018-07-01 | 2020-01-31 | 48.65 Lakhs |
| 6 | Search for novel anti-platelet and anti-thrombin peptides from Indian viper venom (Daboia russelii): Purification, characterization and evaluation of its anti-thrombotic potential | Department of Biotechnology, Ministry of Science and Technology, Govt. of India | 2018-11-01 | 2021-10-31 | 60.79 Lakhs |
| 7 | Isolation, identification and characterization of marker proteins from the Venom of Naja kaouthia and Bungarus fasciatus of North East India for Development of Rapid Diagnostic Tool for Identification of snakebite in North East India. | ICMR, Govt. of India | 2017-11-01 | 2020-10-31 | 38.53 Lakhs |
| 8 | Study for label free optical detection of snake venom protein using Surface Plasmon Resonance technique | Department of Science and Technology, Govt. of India | 2018-06-01 | 2019-05-31 | 47.521 lakhs |
| SL | Awards | Year |
|---|---|---|
| 1 | Chancellor’s Gold Medal, Rajiv Gandhi University | 1999 |
| 2 | Gold Medal in PG, Rajiv Gandhi University | 1999 |
He has joined PhD in July 2018. His area of research involves snake venom toxinology. He has qualified national and state level exams such as CSIR NET JRF (2017) and SLET (2017).
He has joined his Ph.D. in July 2019. He is working on the exploration of the therapeutic potential of north-east Indian Naja kaouthia venom peptides against cardiovascular diseases. He has qualified for national-level exams such as GATE (2019) and Joint CSIR- UGC NET JRF (2019). [WEB SITE ]
She has joined PhD in July 2017. Her area of research involves identification and characterization of cytotoxic proteins from snake venom. She has qualified national level exam such as UGC-NET JRF (2016).
He has joined his Ph.D. in July 2019. His area of research involves the identification of medicinal plants used against Ophidian envenomation. He has qualified for national and state-level exams such as GATE (2019), SLET (2019), and Joint CSIR-UGC NET (2020, and 2021).
She joined Ph. D. in September 2020. Her research work deals with the bioremediation of crude oil-contaminated soil. She has qualified for GATE XL 2019, GATE XL 2020, SLET 2019, ICAR NET 2021.
She joined her Ph. D. in September 2020. Her research work deals with the study of ticks (Acarology) and tick-borne diseases. She has qualified for GATE XL 2020, SLET 2021, and UGC-NET (2022).
She joined her Ph.D. in January 2023. She is working on designing and validation of aptamers against venom proteins. She has qualified for GATE 2021.
She joined the lab in January 2024. She has qualified for Joint CSIR UGC NET LS 2022 & NE SLET 2022.
Title of thesis: Studies on the crude venom and purified three-finger toxin of Naja kaouthia from North East India.
Award of PhD Degree: 2016
Title of thesis: Proteomics of Indian Daboia russelii venom (Irula) and characterization of a major protein
Award of PhD Degree: 2016
Title of thesis: Identification and characterization of thrombin inhibitors from the salivary gland of tick (Haemaphysalis bispinosa)
Award of PhD Degree: 2016
Title of thesis: Expression and characterization of recombinant Flavikunin: A Kunitz-typre serine protease inhibitor from the venom of Bungarus flaviceps
Award of PhD Degree: 2019
Title of thesis: Studies on proteomics of Naja kaouthia venom (North East Indian origin) and role of Cysteine-Rich Secretory Protein in elapid induced inflammation
Award of PhD Degree: 2020
Thesis title: Studies on neutralization of some biochemical and biological activities of Daboxin P and Big Four venoms by selected bioactive compounds of medicinal plants and rationally designed aptamers
Award of PhD Degree: 2022
Title of thesis: Identification and characterization of an antiplatelet protein from Daboia russelii venom and understanding its molecular mechanism
Award of PhD Degree: 2023
Title of thesis: Studies on crude venom of Indian green pit vipers and characterization of a haemostatically active protein from Trimeresurus erythrurus venom
Award of PhD Degree: 2023
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Worked as JRF in DBT Twinning project
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Worked as JRF in ICMR sponsored project
Integrated M.Sc Student. Batch 2010-2015.
Title of Project: Molecular cloning and expression of a novel thrombin inhibitor isolated from tick (Haematophysalis bispinosa).
Integrated M.Sc. student. Batch 2012-2017.
Title of Project: Expression and characterization of Haemathrins: cleavable inhibitor from tick (Haematophysalis bispinosa).
Integrated M.Sc Student. Batch 2013-2018.
Title of Project: Purification and partial characterization of a PLA2 enzyme from Naja kaouthia venom of North-East India.
Integrated M.Sc Student. Batch 2014-2019
Integrated M.Sc Student. Batch 2015-2020
Integrated M.Sc Student. Batch 2017-2022
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M.Sc Student. Batch 2008-2010.
Title of Project: Molecular cloning and expression of a gene encoding proteolytic enzyme from Paenibacillus tezpurensis sp. nov. AS-S24-II.
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M.Sc Student. Batch 2009-2011
M.Sc Student. Batch 2009-2011
Title of Project: Partial purification and characterization of a phospholipase A2 from Asian spitting cobra (Naja siamensis).
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M.SC Student. Batch 2009-2011.
Title of project: A study on the medicinal plants used by the mizo community for treatment of snakebite patients in Mizoram.
M.Sc Student. Batch 2010-2012.
Title of Project: Non cross reactive phospholipase A2 from Bungarus fasciatus venom: purification and partial characterization.
M.Sc Student. Batch 2010-2012.
Title of Project: Cloning and expression of a bacterial keratinase.
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M.Sc Student. Batch 2011-2013.
Title of Project: Purification and characterization of a three finger toxin protein from Naja siamensis venom.
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M.Sc Student. Batch 2011-2013.
Title of Project: Morphological and molecular characterization of tick.
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M.Sc Student. Batch 2012-2014
Title of Project: Partial purification and characterization of a protein from Daboia russelii venom.
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M.Sc Student. Batch 2012-2014.
Title of Project: Partial purification and characterization of a protein from Naja siamensis venom.
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M.Sc Student. Batch 2013-2015.
Title of Project: Purification and partial characterization of L-amino acid oxidase from Indian Daboia russelii venom.
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M.Sc Student. Batch 2014-2016.
Title of Project: Antivenomics and partial characterization of a PLA2 purified from Indian Daboia russelii venom.
M.Sc Student. Batch 2014-2016.
Title of Project: Purification and partial characterization of a PLA2 from Daboia russelii (Irula) venom.
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M.Sc Student. Batch 2015-2017.
Title of Project: Purification and characterization of a Phospholipase A2 from Echis carinatus carinatus venom.
M.Sc Student. Batch 2016-2018.
Title of Project: Cloning, expression and characterization of kunitz type serine protease inhibitor (KSPI) identified in Bungarus flaviceps (Red-headed krait) venom.
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M.Sc Student. Batch 2017-2019.
Title of Project: Isolation and partial characterization of phospholipase A2 enzyme from Naja kaouthia venom.
M.Sc Student.Batch 2017-2019.
Title of Project: Purification and characterization of a protein from the venom of Indian Daboia russelii.
M.Sc Student. Batch 2018-2020
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M.Sc Student. Batch 2018-2020
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M.Sc Student. Batch 2019-2021
M.Sc Student. Batch 2016-2018.
Title of Project: Development of venom protein conjugated nanoparticle and its characterization.
MBI19020
Batch 2019-2024
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Phone: 03712275412
Mobile:
TU Email: doley(AT)tezu.ernet.in
Other email: doleyr(AT)gmail.com
Integrated MSc
MSc
PhD