Research Interest

Position held

Education qualification

    B. Sc. (Chemistry Hons) from Bananas Hindu University, Varanasi in 1990 with first class first position.

    M. Sc. (Biochemistry) from Bananas Hindu University, Varanasi in 1992 with first class first position.

    Ph. D.  from Burdwan University, Burdwan in 1998 (Work was done at Department of Biochemistry, Burdwan Medical College).

    D. Sc. (Biotechnology) from Calcutta University, Kolkata in 2017


Ongoing projects

Sl. Title Sponsored Start date End date Fund
1 Studies on epidemiology, hospital management of snakebite, and standardization of laboratory tests for assessment of efficacy and quality control of commercial antivenom manufactured in India and in ASEAN countries. DST-SERB (Under ASEAN) 2018-02-01 2021-01-31 46,43,800.00
2 Development of functionalized nanoparticles-based novel diagnostic kit for the detection of species-specific snake envenomation DBT Tata Innovation Fellowship 2018-04-01 2021-03-31 18,00,000.00
3 Development of snake venom toxins-targeted specific novel anti-venom BIRAC-PACE 2018-06-01 2019-12-31 38,00,000.00
4 Studies onsignal transduction mechanism(s) of neurotrophin molecules from Indian cobra (Najanaja) and Russell’s Viper (Daboiarusselii) venoms in cultured neuronal cells and their functional significance SERB, New Delhi 2018-12-01 2021-11-30 39,29.600.00
5 Studies on country specific polyvalent Snake Venom Antiserum for Sri Lanka developed by PremiumSerums & Vaccines Pvt.Ltd: Purity assessment and immuno cross-reactivity analyses Premium Serum & Vaccines Pvt. Ltd., Pune 2019-04-01 2020-03-31 5,09,152.00
6 Pharmacological studies of recombinant and mutant fibrin(ogen)olytic protease(s) for the prevention and/or treatment of hyperfibrinogenemia associated cardiovascular disorders DBT, New Delhi 2018-09-01 2020-03-31 26,04,400.00

Completed projects

SL Title Sponsored Start date End date Fund
1 Identification of some local herbs and plants of Assam for antisnake venom activity. UGC, New Delhi 1999-04-01 2020-03-31 15,000.00
2 Isolation, characterization and commercial applications of biosurfactant produced by thermophilic and mesophilic bacteria from the soil samples of Assam, India. ONGC-CPBT 1999-10-01 2008-03-31 18890000.00 (to the Department)
3 Isolation, characterization and biological activities of phospholipase A2 enzyme from Indian monocled cobra (Naja kaouthia) venom. UGC, New Delhi 2001-07-01 2004-06-30 612000.00
4 Isolation, biochemical and pharmacological characterization of pro-coagulant and anti-coagulant proteins from Indian Russell’s viper (Daboiarusselli) venom. UGC, New Delhi 2005-03-01 2008-02-29 867000.00
5 Exploration of potential microbes from North-east India for the production of three commercially important enzymes- protease, amylase and cellulose. DBT, New Delhi 2005-11-01 2008-10-31 894000.00
6 Microbial enzymes, biosurfactant and probiotics (under SAP, DRS-I). UGC, New Delhi 2009-04-01 2014-03-31 42,00000.00 (to the Department)
7 Strengthening of biotechnology teaching, research, and training in Assam with special reference to Tezpur University DBT special project , New Delhi 2009-10-01 2014-09-30 29800000.00(to the Department)
8 Demonstration of novelty of protease produced by selected bacteria isolated from North-east India. DBT, New Delhi 2010-09-01 2011-08-31 714000.00
9 Assessment of thrombolytic potential and anticancer activity of fibrinolytic enzymes purified from Russell’s viper venom and bacteria isolated from NE-India DBT, New Delhi 2011-04-01 2014-09-30 12086000.00
10 Proteomics study of aromatic hydrocarbon degradation enzymes of some selected bacterial strain prospecting strategies for environmental bioremediation ONGC-CPBT, Tezpur University 2014-05-01 2016-04-30 706000.00
11 Application of snake venom toxins labeled with functionalized nanoparticles for detecting endogenous targets in cells and ex vivo tissues with prospects for the development of novel diagnostic and therapy tools DBT , New Delhi under Indo-Russia collaborative project 2014-12-01 2017-11-30 4560000.00
12 Discovering novel drug formulations from non-toxic, potent anticoagulant components of snake venom for the prevention and/or treatment of cardiovascular disease (CVD). DBT, New Delhi under National Bioscience Award for Career Development-2013 2014-12-01 2018-03-31 150000.00
13 Assessment of purity and contaminating protein(s) in equine polyvalent anti snake venom manufactured by Premium Serum & Vaccines Pvt. Ltd., Pune Premium Serum & Vaccines Pvt. Ltd., Pune 2017-04-01 2018-03-31 4,05,750.00
14 Development of a cost-effective, novel antithrombotic anticoagulant herbal drug and standardization of its biomarker assisted quality Control BIRAC-BIG project 2016-10-01 2018-06-30 4975000.00
15 Venomics and antivenomics of Indian Cobra and Russell's viper: implications in drug discovery and quality control of antivenoms DBT, New Delhi under Unit of Excellence in NER-2013 scheme 2014-12-01 2018-12-31 13220000.00

Publication

  1. Islam, T., Madubala, D., Mukhopadhyay, R., Mukherjee, A. K., Transcriptomic and functional proteomics analyses to unveil the common and unique pathway(s) of neuritogenesis induced by Russell’s viper venom nerve growth factor in rat pheochromocytoma neuronal cells, Expert Review of Proteomics , 18(6), 463-481, 2021, 3.614, Click Here (DOI)
  2. Islam, T., Majumder, M., Kalita, B., Bhattacharjee, A., Mukhopadhyay, R., Mukherjee, A. K., Transcriptomic, proteomic and biochemical analyses reveal a novel neuritogenesis mechanism of Najanaja venom α-elapitoxin post binding to TrkA receptor of rat pheochromocytoma cells, Journal of Neurochemistry , 12020;00: 1–26 , 2020, 4.830, Click Here (DOI)
  3. Puzari, U., Mukherjee, A. K., Recent developments in diagnostic tools andbioanalytical methods for analysis of snake venom: A critical review, Analytica Chimica Acta , 1137, 208-224, 2020, 5.977, Click Here (DOI)
  4. Patra, A. and Mukherjee, A.K., Assessment of snakebite burdens, clinical features of envenomation, and strategies to improve snakebite management in Vietnam., Acta tropica, 216, p.105833, 2021, 2.650, Click Here (DOI)
  5. Mukherjee, A. K., Species-specific and geographical variation in venom composition of two major cobras in Indian subcontinent: Impact on polyvalent antivenom therapy, Toxicon , 188, 150-158 , 2020, 2.270, Click Here (DOI)
More Publication >>

Books

  1. Biotechnology in health care: challenges and promises for us in the next millennium, Indian Chemical Industry-Opportunities Unlimited, 2000, Dept. of Chemicals and Petrochemicals, Govt. of India
  2. Pharmacological assessment of medicinal plants to ascertain their anti-snake venom activity, Ethnomedicine of North-East India: Protection, Utilization and Conservation, 2003, National Institute of Science Communication and Information Resources, CSIR, New Delhi
  3. Microbial Surfactants and their Potential Applications: An Overview, Biosurfactants, 2010, Landes Bioscience, Texas, USA
  4. An updated inventory on properties, pathophysiology and therapeutic potential of snake venom thrombin-like proteases, Proteases in Health and Disease-Advances in Biochemistry in Health and Disease Volume 7 (ISBN 978-1-4614-9233-7), 2013, Springer
  5. Pathophysiological significance and therapeutic implications of Russell’s Viper venom proteins and peptides affecting blood coagulation, Snake Venoms and Envenomation: Modern Trends and Future Prospects, 2016, Nova Science Publishers: New York
  6. Anticoagulant and membrane damaging properties of snake venom phospholipase A2 enzymes, Handbook of Toxinology, volume – snake venom, 2017, Springer Nature: Netherlands
  7. A Brief Appraisal on Russell’s Viper Venom (Daboia russelii) Proteinases, Handbook of Toxinology, volume– snake venom, 2017, Springer Nature: Netherlands
  8. Conjugates of α-Cobratoxin with CdSe Quantum Dots: Preparation and Biological Activity, Nano Hybrids and Composites, 2017, (online book chapter)
  9. Snake Envenomation: Therapy and Challenges in India, Section V: Global Approaches to Envenomation and Treatments, Handbook of Venoms and Toxins of Reptiles, 2020, CRC Press, USA (accepted manuscript in press)
  10. An Overview of Raw Starch Digesting Enzymes and Their Applications in Biofuel Development., Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment, 2021, Springer

Awards

SL Awards Year
1 Banaras Hindu University (B.H.U.) cash prize recipient for securing first class first position in B. Sc. (Chemistry Hons.) Examination 1990
2 Qualified the UGC-CSIR NETfor Junior Research Fellowship (JRF) and eligibility for lectureship in Life Sciences in Colleges and Universities of India 1991
3 B. H.U. Gold Medal for securing first class first position in M. Sc examination 1992
4 Certificate of Honor awarded by the Association of Medical Biochemists of India 1995
5 Young Scientist Gold Medal awarded by Zoological Society of India 1995
6 Young Scientist Gold Medalawarded by Physiological Society of India 1997
7 Young Scientist Award recipient in Medical and Veterinary Sciences section of Indian Science Congress Association 1999
8 BOYSCAST Fellowship (2002-2003) from the Department of Science and Technology (DST), Ministry of Science and Technology, Govt. of India for advance research and training at USA 2001
9 International Travel Award from the Department of Biotechnology, Govt. of India for presenting papers in an International conference at Seville, Spain 2007
10 Sectional Chairman, International CME & Conference on Snakes, Venom and Snakebite, Angamaly, Kerala 2008
11 Best Research Worker Award of Tezpur University 2008
12 Sectional Chairman, 54th Technical Meeting of Assam Science Society, Tezpur University 2009
13 Sectional Chairman, International Symposium on Environmental Pollution, Ecology and Human Health, S.V. University, Tirupati 2009
14 Co-Chairman, National Symposium on “Recent advances in snake venom research and snakebite therapy: national and International Perspectives”, Tezpur University 2009
15 Executive Committee Member, DBT Nodal Cell for Medical Colleges and Biomedical Research Institute of NE India, Department of Biotechnology, Ministry of Science and Technology, Govt. of India 2010
16 Dr. J. N. Baruah Memorial Science Award, 2010 in Biological Sciences by Assam Science Society, India 2010
17 Co-Chairman, National Conference on “Animal, Microbial, and Plant Toxins & Snakebite Management” held at IICB, Kolkata and KPC Medical College and Hospital, Kolkata 2010
18 Sectional Committee Member (2011-2012), New Biology section, Indian Science Congress Association, Kolkata 2010
19 DBT-CREST (Cutting Edge Research Enhancement and Scientific Training) Award 2010-11from the Department of Biotechnology, Ministry of Science and Technology, Govt. of India for advance training in the field of proteomics and drug discovery at UNC, USA 2011
20 Member, Star College Scheme, Department of Biotechnology, Ministry of Science and Technology, Govt. of India (2011-2014) 2011
21 Sectional Co-Chairman and Member of the Scientific Organization committee 17th World Congress on Venoms and Toxins organized by International Society on Toxinology, Honolulu, Hawaii, USA 2012
22 Unit of Excellence Award (2013) in NER of India by the Department of Biotechnology, Ministry of Science and Technology, Govt. of India 2013
23 Session Co-Chairman, Society of Biological Chemists (India) meeting of NE chapter, February 22, 2014 at North-East Institute of Science and Technology (CSIR), Jorhat 2014
24 National Bioscience Award for career Development-2013 by Department of Biotechnology, Ministry of Science and Technology, Govt. of India 2014
25 Sreenivasaya Memorial Award-2014for outstanding contribution inBiochemistry and allied sciences by the Society of Biological Chemists (India), held at KIIT University, Bhubaneswar, December, 2014 2014
26 Cama Memorial Travel Grant for presenting a paper in the 18th World Congress of International Society on Toxinology, Oxford, UK from Society of Biological Chemists (India), Bangalore 2015
27 “International Travel Grant” for presenting a paper in the 18th World Congress of International Society on Toxinology, Oxford, UK awarded by Department of Science and Technology (DST), Ministry of Science and Technology, Govt. of India 2015
28 Sectional Co-Chairman, TSICO2015, 5th National Conference of Toxinological Society of India, organized by Little Flower Hospital, Cochin 2015
29 Sectional Chairman, Recent Developments in Medical Biotechnology and Structure Based Drug Designing [RDMBSBDD-2015] organized by IIT, Guwahati 2015
30 Sectional Committee Member, Medical (including Physiology) Section, Indian Science Congress Association, Kolkata (2016-2017) 2016
31 Chairman, National seminar on “Snake Venom Research and Snakebite Therapy: National and International Perspectives (SnakSymp2016)”, 22 to 24 November, 2016, Tezpur University. 2016
32 Sectional Co-Chairman, New Biology Section, 104th Indian Science Congress, S. V. University, Tirupati, 3-7 January, 2017 2017
33 Sectional Committee Member, New Biology Section, Indian Science Congress Association, Kolkata (2017-2018) 2017
34 Awarded “Doctor of Science (D. Sc.)” in Biotechnology by Calcutta University 2017
35 Certificate of Appreciation by Tezpur University in recognition and appreciation of academic achievements. 2018
36 Received “Visitor’s Award for Research in Basic and Applied Sceinces-2018” from honorable President of India at Rashtrapati Bhawan on 2 May, 2018 2018
37 Awarded “Tata Innovation Fellowship (2017-18)” by Department of Biotechnology, Ministry of Science and Technology, Govt. of India 2018
38 Elected Fellow Royal Society of Biology (FRSB)”, United Kingdom. 2018
39 INSA Teachers Award-2018 from Indian National Science Academy (INSA), New Delhi 2018
40 Received “Indian Council of Medical Research Prize for Biomedical Research Conducted in Underdeveloped Areas” (Prize for the year 2017) from ICMR, New Delhi 2018
41 Professor Sohail Ahmad Award-2018 from Indian Academy of Biomedical Sciences, Lucknowfor outstanding research contribution in the field of Biomedical Sciences (basic research) 2018
42 Expert Member, Department of Biotechnology, Ministry of Science and Technology, Govt. of India -NER Technical Expert Committee in the area of Knowledge Generation and Discovery Research, New Tools, and Techniques 2018
43 Nominated and sponsored by Ministry of Human Resource Development (MHRD), Govt. of India for participation in three weeks programme on the “Leadership-for-Academicians Programme (LEAP)”. 2019
44 National Task Force Expert Member “ICMR-National Task Force for Research on Snake Bite in India”, Indian Council of Medical Research, Govt. of India 2019
45 Nominated Fellow, West Bengal Academy of Science and Technology, Kolkata, West Bengal, India 2019
46 Expert Member, National Advisory Committee on Snakebite Envenoming, Department of Biotechnology, Ministry of Science and Technology, Govt. of India 2019
47 Core Member, Expert committee of DST-FIST program of Department of Science and Technology, Ministry of Science and Technology, Govt of India. 2020
48 Expert Member, World Health Organization 2021
49 Outstanding Professor in the Faculty of Biological Sciences, The Academy of Scientific and innovative Research (AcSlR) 2021
50 Member of Senate, Central Institute of Technology Kokrajhar, Assam. 2021
51 Editorial Board Member, Toxicon and Toxicon-X (Elsevier journals) published by International Society of Toxinology. 2021
52 Elected Fellow, Indian Academy of Sciences, Bangalore 2022
53 SFE-ZANDU Award – 2022 by Society for Ethnopharmacology, Kolkata, India 2022

Research Scholars

Bhabana Das, M.Sc.
Bhabana Das, M.Sc. Contact: 7002836075 Email: bhabana@tezu.ernet.in

Post graduate Degree in Zoology,

Gauhati University, Guwahati.

Current Position: Junior Research Fellow (CSIR).

Research interest:Biochemical and Proteomic analysis of Scorpion venom.

Nitisha Boro, M.Sc.
Nitisha Boro, M.Sc. Contact: 7896774952 Email: nitisha@tezu.ernet.in

Post graduate Degree in Biotechnology,

Bodoland University, Kokrajhar.

Current Position: Junior Research Fellow (CSIR)

Research interest: Bacterial recombinant protease and its industrial application.

Dev Madhubala, M.Sc.
Dev Madhubala, M.Sc. Contact: 9471351315 Email: dmadhu@tezu.ernet.in

Post graduate Degree in Life Science (Biochemistry),

Central University of Punjab, Bathinda.

Current Position:  Junior Research Fellow(DST- SERB)

Research interest:Characterization of Nerve growth factor from Snake venom.

 

Upasana Puzari, M.Sc.
Upasana Puzari, M.Sc. Contact: 9954129598 Email: upa2019@tezu.ernet.in

Postgraduate in Biotechnology and Bioinformatics ,

Dibrugarh University, Dibrugarh.

Current Position: Research Scholar

Research interest : Development of snake venom detection kit.

 

Hirakjyoti Kakati, M.Sc.
Hirakjyoti Kakati, M.Sc. Contact: 9678984357 Email: hirak19@tezu.ernet.in

Post graduate Degree in Zoology,

Assam University, Silchar.

Current Position: ICMR-SRF

Research interest:  Proteomics and glycoproteomics analysis  of snake venom as well as epidemiology of snakebite in North-Eastern Region of India


Project Students


M.Sc. students


Integrated M.Sc. students


Alumni

Activity Details

SL Title Year Type