Relevant Discipline: Pharmaceutical Sciences
Theme: Antimalarial Drug Discovery
Recommended By: Hans Raj Bhat
Topic/sub-topic |
Resources |
Annotation |
Pathophysiology of Malaria
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1.(Video) Malaria parasite life cycle
(1)https://www.youtube.com/watch?v=bMK1KTXvWw0 (Time: 2.29 Min) (2) https://www.youtube.com/watch?v=bfQVbfX0y3I (Time: 1.55 Min)
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Description: Transmission of Plasmodium parasite from females Anopheles mosquitoes to human. Rapidly multiply in the liver and then in red blood cells (RBC) of the infected person.
Suitable for: Pharmacy and Medical Students (UG and PG)
Learning outcome: Pathophysiology of malaria parasite. How the malaria parasite spread from mosquito to human and infected the liver and RBC. |
2.(Website) |
Description:Malarial illness is caused by the infection of the red blood cells by the asexual forms of the malaria parasite and the involvement of the red cells makes malaria a potentially multisystem disease.
Suitable for: Pharmacy and Medical Students (UG and PG)
Learning outcome: Understanding the pathophysiology of Malaria parasite from mosquitoes to human involvement of RBC and understand their symptoms such as fever. |
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3.(E Book) http://www.digitalbookindex.org/_search/search010histmedicalmalariaa.asp http://openaccessebooks.com/vector-borne-diseases-treatment.html |
Description: Vector bone diseases are transmitted from infected arthropod species such as mosquitoes to human and their Safety measures and prevention. Malaria:etiology,pathology,diagnosis, prophylaxis and treatment.
Suitable for: Pharmacy and Medical Students (UG and PG)
Learning outcome: How the malaria parasite spread from mosquito to human and How to stop mosquito bites by the use of mosquito repellent creams, liquids, coils, mats etc. |
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4.(Data Base) |
Description: Both parasite and host-related factors contribute to the pathogenicity of the severe forms of the malaria disease and contribute to the vascular damage and the consequent excessive inflammatory/immune response of the host.
Suitable for:Pharmacy and medical Students (UG and PG)
Learning outcome: How the malaria parasites spread from blood to different part of body and their severe effect on RBC and immune system. |
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5.(E-Journal) https://malariajournal.biomedcentral.com/articles/10.1186/s12936-018-2389-z http://www.bloodjournal.org/content/117/2/381?sso-checked=true https://www.nature.com/articles/srep41722
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Description: Reduction of malaria prevalence after introduction of artemisinin-combination-therapy (Hybrid therapy) and development of new drug by combination of two drugs. Suitable for:Pharmaceutical students (M. Pharm and Ph.D.)
Learning outcome: Drug design and development of new drug by the combination of two drug molecules, to reduce the drug resistance and learn the advantage of combination therapy. |