E-Resource > Pathophysiology of Malaria                                                                                                                                                                                                                  Click here to download

Topic: Pathophysiology of Malaria

Relevant Discipline: Pharmaceutical Sciences

Theme: Antimalarial Drug Discovery

          Recommended By: Hans Raj Bhat

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 Pathophysiology of Malaria


 

1.(Video)

Malaria parasite life cycle

 

(1)https://www.youtube.com/watch?v=bMK1KTXvWw0 (Time: 2.29 Min)

(2) https://www.youtube.com/watch?v=bfQVbfX0y3I (Time: 1.55 Min)

 

Description: Transmission of Plasmodium parasite from  females Anopheles  mosquitoes to human. Rapidly multiply in the liver and then in red blood cells (RBC) of the infected person.

 

Suitable for: Pharmacy and Medical Students (UG and PG)

 

Learning outcome: Pathophysiology of malaria parasite. How the malaria parasite spread from mosquito to human and infected the liver and RBC.

2.(Website)

https://www.malariasite.com/pathophysiology/

http://www.malaria.com/questions/pathophysiology-malaria

Description:Malarial illness is caused by the infection of the red blood cells by the asexual forms of the malaria parasite and the involvement of the red cells makes malaria a potentially multisystem disease.

 

Suitable for: Pharmacy and Medical Students (UG and PG)

 

Learning outcome: Understanding the pathophysiology of Malaria parasite from mosquitoes to human involvement of RBC and understand their symptoms such as fever.

3.(E Book)

http://www.digitalbookindex.org/_search/search010histmedicalmalariaa.asp

http://openaccessebooks.com/vector-borne-diseases-treatment.html

Description: Vector bone diseases are transmitted from infected arthropod species such as mosquitoes to human and their Safety measures and prevention. Malaria:etiology,pathology,diagnosis, prophylaxis and treatment.

 

 

Suitable for:  Pharmacy and Medical Students (UG and PG)

 

Learning outcome:  How the malaria parasite spread from mosquito to human and How to stop mosquito bites by the use of  mosquito repellent creams, liquids, coils, mats etc.

4.(Data Base)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499994/

https://www.britannica.com/science/malaria

Description: Both parasite and host-related factors contribute to the pathogenicity of the severe forms of the malaria disease and  contribute to the vascular damage and the consequent excessive inflammatory/immune response of the host. 

 

Suitable for:Pharmacy and medical Students (UG and PG)

 

Learning outcome: How the malaria parasites spread from blood to different part of body and their  severe effect on RBC and immune system.

5.(E-Journal)

https://malariajournal.biomedcentral.com/articles/10.1186/s12936-018-2389-z  

http://www.bloodjournal.org/content/117/2/381?sso-checked=true

https://www.nature.com/articles/srep41722

 

Description: Reduction of malaria prevalence after introduction of artemisinin-combination-therapy (Hybrid therapy) and development of new drug by combination of two drugs.

Suitable for:Pharmaceutical students (M. Pharm and Ph.D.)

 

Learning outcome: Drug design and  development  of new drug by the combination of two drug molecules, to reduce the drug resistance and learn the advantage of combination therapy.

          Recommended by:Hans Raj Bhat
          Affiliation: Assistant Professor ,Pharmaceutical Sciences
          Institution:Dibrugarh University
          Specialization:Pharmaceutical Chemistry
          Email-id:hennirina@gmail.com

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