More Publication of Mohini M. Konai
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- More Publication of Mohini M. Konai
More Publication of Mohini M. Konai
Das, S.; Poudel, R.; Dutta, K.; Konai, M. M., A Review on Small Molecular Mimics of Antimicrobial Peptides with An Emphasis on Structure-Activity-Relationship Perspective, RSC Medicinal Chemistry, 16, 2025, , Click Here (DOI)
Dutta, K.; Das, S.; Poudel, R.; Karak, N.; Konai, M. M, Graphene oxide/epoxy nanocomposite material for antibacterial drug delivery application, Journal of Drug Delivery Science and Technology, 107592, 2025, , Click Here (DOI)
Dominguez-Cisneros, H.; Konai, M. M.; Kim, C.; Rana, N.; Feltzer, R.; Janardhanan, J.; El-Araby, A. M.; Nguyen, V. T.; Fisher, J. F.; Chang, M.; Mobashery, S., Antibacterial Benzimidazole-2-Methanamines as Allosteric Modulators of Streptococcus pneumoniae Penicillin-Binding Protein 2x, Journal of Medicinal Chemistry, , 2025, , Click Here (DOI)
Dutta, K.; Das, S.; Poudel, R.; Konai, M. M., Tyrosine-Mediated Facile Synthesis of a Graphene Oxide-Silver Nanocomposite for Antibacterial Applications, ACS Applied Nano Materials, , 2025, , Click Here (DOI)
Roversi, D.; Vaezi, Z.; Bortolotti, A.; Di Stefano, C.; Bonacorsi, S.; Santucci, V.; Aisenbrey, C.; Konai, M. M.; Acharya, Y.; Khosravi-Far, R.; Bechinger, B.; Haldar, J.; Stella, L., The “Sand in a gearbox” effect of antimicrobial peptides: beyond pore formation on model membranes and real bacteria cells, JOURNAL OF PEPTIDE SCIENCE, 30, 2024, 30, Click Here (DOI)
Bortolotti, A.; Troiano, C.; Bobone, S.; Konai, M. M.; Ghosh, C.; Bocchinfuso, G.; Acharya, Y.; Santucci, V.; Bonacorsi, S.; Di Stefano, C.; Haldar, J.; Stella, L. , Mechanism of lipid bilayer perturbation by bacterial membrane-active small molecules. , Biochimica et Biophysica Acta (BBA)-Biomembranes, 184079, 2023, 184079, Click Here (DOI)
Thakur, V.; Thakur, V.; Aguila, B.; Slepak, T.; Wang, M; Song, W.; Konai, M. M.; Mobashery, S.; Chang, M.; Rana, A.B.; Wang D.; Tiburcio de Freitas, J.; Gultekin, S.H.; Welford, S.M.; Ivan, M. E.; Bedogni, B. , Targeting extracellular matrix remodeling sensitized glioblastoma to ionizing radiation., Neuro-Oncol. Adv. , , 2022, 7.51, Click Here (DOI)
Masitas, C.; Peng, Z.; Wang, M.; Konai, M.M.; Avila-Cobian, L.; Lemieux, L. Hovanesian, J.; Grady, J.; Mobashery, S.; Chang, M., Matrix metalloproteinase-14 as an instigator of fibrosis in human pterygium and its pharmacological intervention., ACS Pharmacol. Transl. Sci., 5(555-561), 2022, 4.88, Click Here (DOI)
Peng, Z.; Konai, M.M.; Avila, L.; Wang, M.; Mobashery, S.; Chang, M. , . MMP-1 and ADAM10 as targets for therapeutic intervention in idiopathic pulmonary fibrosis., ACS Phamacol. Transl. Sci., 5(548-554), 2022, 4.88, Click Here (DOI)
Peng, Z.; Nguyen, T. T.; Wang, M.; Anderson, B.; Konai, M. M.; Schroeder, V. A.; Wolter, W. R.; Page-Mayberry, T.; Peterson, C. E.; Mobashery, S.; Chang, M. , Proteomics Identification of Targets for Intervention in Pressure Ulcers., ACS Chemical Biology, 6(1357-1363), 2022, 4.634, Click Here (DOI)
Garg, P.; Konai, M. M.; Tabbasum, K.; ; Haldar, J. , Cyclam-based Antibacterial Molecule Eradicates Gram-negative Superbugs with Potent Efficacy against Human Corneal Infection., Invest. Ophthamol. Vis Sci., 61(3260), 2020, 4.799, Click Here (DOI)
Konai, M. M.; Barman, S.; Issa, R.; MacNeil, S.; Adhikary, U.; De, K.; Monk, P. N.; Haldar. J. , Hydrophobicity Modulated Antibacterial Small Molecule Eradicates Biofilm with Potent Efficacy against Skin-infections. , ACS Infect. Dis. , 6(703-714), 2020, 5.084, Click Here (DOI)
Konai, M. M.; Pakrudheen, I.; Barman, S.; Sharma, N.; Tabbasum, K.; Garg, P.; Haldar, J. , Cyclam-based Antibacterial Molecule Eradicates Gram-negative Superbugs with Potent Efficacy against Human Corneal Infection., Chem. Commun., 56(2147-2150), 2020, 6.065, Click Here (DOI)
Konai, M. M.; Haldar, J. , Lysine-Based Small Molecule Sensitizes Rifampicin and Tetracycline against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa. , ACS Infect. Dis., 6(91-99), 2020, 5.084, Click Here (DOI)
Barman, S.; Konai, M. M.; Samaddar, S.; Haldar, J., Amino Acid Conjugated Polymers: Antibacterial Agents Effective against Drug-Resistant Acinetobacter baumannii with No Detectable Resistance., ACS Appl. Mater. Interfaces , 11(33559-33572), 2019, 10.38, Click Here (DOI)
Konai, M. M.; Bhattacharjee, B.; Ghosh, S.; Haldar, J. , Recent Progress in Polymer Research to Tackle Infections and Antimicrobial Resistance., Biomacromolecules , 19(1888-1917), 2018, 6.988, Click Here (DOI)
Konai, M. M.; Samaddar, S.; Bocchinfuso, G.; Santucci, V.; Stella, L.; Haldar, J., Selectively Targeting Bacteria by Tuning the Molecular Design of Membrane-active Peptidomimetic Amphiphiles. , Chem. Commun. , 54(4943-4946), 2018, 6.065, Click Here (DOI)
Konai, M. M.; Adhikary, U, Haldar, J. Design and Solution Phase Synthesis of Membrane Targeting Lipopeptides with Selective Antibacterial Activity, Chem. Eur. J., 23(12853 -12860), 2017, 5.02, Click Here (DOI)
Challa, C.; Ravindran, J.; Konai, M. M.; Varughese, S.; Jacob, J.; Kumar, B. S. D.; Haldar, J.; Lankalapalli, R. S. , Expedient Synthesis of Indolo[2,3‑b]quinolines, Chromeno[2,3‑b]indoles, and 3‑Alkenyl-oxindoles from 3,3′-Diindolylmethanes and Evaluation of Their Antibiotic Activity against Methicillin-Resistant Staphylococcus aureus. , ACS Omega , 2(5187-5195), 2017, 4.132, Click Here (DOI)
Konai, M. M.; Haldar, J., Fatty Acid Comprising Lysine Conjugates: Anti-MRSA Agents That Display In-vivo Efficacy by Disrupting Biofilms with No Resistance Development., Bioconjugate Chem., 28(1194-1204), 2017, 6.069, Click Here (DOI)
Uppu, D. S. S. M.; Konai, M. M.; Sarkar, P.; Samaddar, S.; Fensterseifer, I. C. M.; Farias-Junior, C.; Paramanandam, K.; Shome, B. R.; Francob, O. L.; Haldar, J. , Membrane-Active Macromolecules Kill Antibiotic-Tolerant Bacteria and Potentiate Antibiotics Towards Gram-negative Bacteria. , PLoS One, 12(e0183263), 2017, 3.752, Click Here (DOI)
Hoque, J.; Konai, M. M.; Sequeira, S. S.; Samaddar, S.; Haldar, J., Antibacterial and Antibiofilm Activity of Cationic Small Molecules with Spatial Positioning of Hydrophobicity: An In Vitro and In Vivo Evaluation., J. Med. Chem., 59(10750-10762), 2016, 8.039, Click Here (DOI)
Ghosh, C.; Konai, M. M.; Sarkar, P.; Samaddar, S.; Haldar, J. , Designing Simple Lipidated Lysine: Bifurcation Imparts Selective Antibacterial Activity., ChemMedChem, 11(2376-2371), 2016, 3.54, Click Here (DOI)
Dowall, S. D.; Bewley, K.; Watson, R. J.; Vasan, S. S.; Ghosh, C.; Konai, M. M.; Gausdal, G.; Lorens, J. B.; Long, J.; Barclay, W.; Garcia-Dorival, I.; Hiscox, J.; Bosworth, A.; Taylor, I.; Easterbrook, L.; Pitman, J.; Summers, S.; Chan-Pensley, J.; , Antiviral Screening of Multiple Compounds against Ebola Virus., Viruses, 8(277), 2016, 5.818, Click Here (DOI)
Hoque, J.; Adhikary, U.; Yadav, V.; Samaddar, S.; Konai, M. M.; Prakash, R. G.; Paramanandham, K.; Shome, B. R.; Sanyal, K.; Haldar, J. , Chitosan Derivatives Active against Multi-Drug-Resistant Bacteria and Pathogenic Fungi: In Vivo Evaluation as Topical Antimicrobials. , Mol. Pharmaceutics, 13(3578-3589), 2016, 5.364, Click Here (DOI)
Uppu, D. S. S. M.; Samaddar, S.; Hoque, J.; Konai, M. M.; Paramanandham, K.; Shome, B. R.; Haldar, J., Side Chain Degradable Cationic-amphiphilic Polymers with Tunable Hydrophobicity Show In-vivo Activity., Biomacromolecules, 17(3094-3102), 2016, 6.988, Click Here (DOI)
Ghosh, C.; Manjunath, G. B.; Konai, M. M.; Uppu, D. S. S. M.; Krishnamoorthy, P.; Shome, B. R.; Ravikumar, R.; Haldar, J., Aryl-alkyl-lysines: Membrane-Active Small Molecules Active against Murine Model of Burn Infection. , ACS Infect. Dis., 2(11–122), 2016, 5.084, Click Here (DOI)
Uppu, D. S. S. M.; Konai, M. M.; Baul, U.; Singh, P.; Siersma, T. K.; Samaddar, S.; Vemparala, S.; Hamoen, L. W.; Narayana, C.; Haldar, J., Isosteric Substitution in Cationic-amphiphilic Polymers Reveals an Important Role for Hydrogen Bonding in Bacterial Membrane Interactions., Chem. Sci., 7(4613-4623), 2016, 9.969, Click Here (DOI)
Hoque, J.; Konai, M. M.; Samaddar, S.; Gonuguntla, S.; Manjunath, G. B.; Ghosh, C.; Haldar, J. , Selective and Broad Spectrum Amphiphilic Small Molecules to Combat Bacterial Resistance and Eradicate Biofilm. , Chem. Commun. , 51(13670-13673), 2015, 6.065, Click Here (DOI)
Konai, M. M.; Haldar, J., Lysine-based Small Molecules That Disrupt Biofilms and Kill Both Actively Growing Planktonic and Non-dividing Stationary Phase Bacteria., ACS Infect. Dis., 1(469-478), 2015, 5.084, Click Here (DOI)
Yarlagadda, V.; Konai, M. M.; Manjunath, G. B.; Prakash, R. G.; Mani, B.; Paramanandham, K.; Ranjan, S. B.; Ravikumar, R.; Chakraborty, S. P.; Roy, S.; Haldar, J., In-vivo Antibacterial Activity and Pharmacological Properties of Membrane Active Glycopeptide Antibiotic (YV11455). , Int. J. Antimicrob. Agents , 25(627-634), 2015, 5.283, Click Here (DOI)
Yarlagadda, V.; Konai, M. M.; Manjunath, G. B.; Ghosh, C.; Haldar, J., Tackling Vancomycin-resistant Bacteria with Lipophilic-vancomycin-carbohydrate Conjugates. J. , Antibiot., 68(302-312), 2015, 3.424, Click Here (DOI)
Ghosh; C.; Manjunath; G. B.; Konai; M. M.; Uppu; D. S. S. M.; Hoque, J.; Krishnamoorthy P.; Shome, B. R.; Haldar, J., Aryl-Alkyl-Lysines: Agents That Kill Planktonic Cells, Persister Cells, Biofilms of MRSA and Protect Mice from Skin-infection., PLoS One, 10:e0144094, 2015, 3.752, Click Here (DOI)
Konai, M. M.; Adhikary, U.; Samaddar, S.; Ghosh, C.; Haldar, J., Structure-activity Relationship of Amino acid Tunable Lipidated Norspermidine Conjugates: Disrupting Biofilms with Potent Activity against Bacterial Persisters., Bioconjugate Chem., 26(2442-2453), 2015, 6.069, Click Here (DOI)
Hoque, J.; Konai, M. M.; Gonuguntla, S.; Manjunath, G. B.; Samaddar, S.; Yarlagadda, V.; Haldar, J. , J. Membrane Active Small Molecules Show Selective Broad Spectrum Antibacterial Activity with No Detectable Resistance and Eradicate Biofilms. , J. Med. Chem., 58(5486-5500), 2015, 8.039, Click Here (DOI)
Yarlagadda, V.; Konai, M. M.; Paramanandam, K.; Nimita, V. C.; Shome, B. R.; Haldar, J., In-vivo Efficacy and Pharmacological Properties of A Novel Glycopeptide (YV4465) against Vancomycin-Intermediate Staphylococcus aureus (VISA)., Int. J. Antimicrob. Agents, 46(446-450), 2015, 5.283, Click Here (DOI)
Hoque, J.; Akkapeddi, P.; Yadav, V.; Manjunath, G. B.; Uppu, D. S. S. M.; Konai, M. M.; Yarlagadda, V.; Sanyal, K.; Haldar, J. , Broad Spectrum Antibacterial and Antifungal Polymeric Paint Materials: Synthesis, Structure-activity Relationship and Membrane-active Mode of Action. , ACS Appl. Mater. Interfaces, 7(1804-1815), 2015, 10.38, Click Here (DOI)
Konai, M. M.; Ghosh, C.; Yarlagadda, V.; Samaddar, S.; Haldar, J., Membrane Active Phenylalanine Conjugated Lipophilic Norspermidine Derivatives with Selective Antibacterial Activity., J. Med. Chem., 57(9409-9423), 2014, 8.039, Click Here (DOI)
Ghosh, C.; Manjunath, G. B.; Akkapeddi, P.; Yarlagadda, V.; Hoque, J.; Uppu, D. S. S. M.; Konai, M. M.; Haldar, J. , Small Molecular Antibacterial Peptoid Mimics: The Simpler The Better!, J. Med. Chem. , 57(1428-1436), 2014, 8.039, Click Here (DOI)
