M
e t a b o l i c D i s e a s e B i o l o g y
L a b o r a t o r y
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Dr.
Suman Dasgupta Assistant
Professor Room
No. 305 Department of Molecular Biology
and Biotechnology Tezpur University Tezpur - 784028 Assam, India Contact:
+91-9954332278 (M), +91-3712-275441 (O) Fax:
+91-03712-267005/267006 |
Academic Qualifications
Ph. D. (Zoology)
in 2011 from Visva-Bharati University, Santiniketan, West Bengal, India.
M. Sc.
(Zoology) in 2004 from University of Calcutta (Ballygunge Science College),
Kolkata, India.
B. Sc.
(Zoology: Hons) in 2002 from University
of Calcutta (B.K.C. College), Kolkata, India.
Assistant
Professor, Department of
Molecular Biology and Biotechnology, Tezpur
University (May 2013-till date).
Quick
Hire Fellow,
Pharmacology Laboratory, Natural
Product Chemistry Division, CSIR-NEIST, Jorhat, Assam (March 2012-April
2013).
Postdoctoral Fellow, Department of Zoology, Visva-Bharati
University, Santiniketan, West Bengal (April 2011-March 2012).
Senior Research Fellow, Department of Zoology, Visva-Bharati University,
Santiniketan, West Bengal (May 2009-March 2011).
Junior Research Fellow, Department of Zoology, Visva-Bharati
University, Santiniketan, West Bengal (March 2006-April 2009).
Insulin
resistance and type 2 diabetes.
Inflammation
and immunity in metabolic diseases.
1.
Units
of Excellence in Biological Sciences at Institution in North East Region
(2016)
by the Department of Biotechnology (DBT), Ministry of Science & Technology,
New Delhi, India.
2.
SERB-Fast
Track Young Scientist (2015) by the Science and
Engineering Research Board (SERB), Department of Science & Technology
(DST), Ministry of Science & Technology, New Delhi, India.
3.
DBT-Innovative
Young Biotechnologist Award (2014) by the
Department of Biotechnology (DBT), Ministry of Science & Technology, New
Delhi, India.
2.
JSPS
Postdoctoral Fellowship (2013) by
the Japan Society for the Promotion of Science, Ministry of Education, Culture,
Sports, Science and Technology, Tokyo, Japan (Not availed).
3.
INSA
medal for Young Scientist (2012) by
the Indian National Science Academy (INSA), Ministry of Science &
Technology, New Delhi, India.
4.
CSIR-NEIST
Quick Hire Fellowship (2012) by the
CSIR-North East Institute of Science and Technology, Jorhat, Assam.
5.
UGC-Dr.
D.S. Kothari Postdoctoral Fellowship (2011) by
the University Grants Commission, New Delhi, India.
6.
CSIR-UGC
National Eligibility Test (NET-JRF, 2006) by the Council of Scientific
and Industrial Research (CSIR)-University Grants Commission (UGC), New Delhi,
India.
7.
UGC-State
Level Eligibility Test (SLET, 2006) by the University Grants Commission
(UGC), New Delhi, India.
8.
CSIR-UGC
National Eligibility Test (NET-LS, 2005) by the Council of Scientific
and Industrial Research (CSIR)-University Grants Commission (UGC), New Delhi,
India.
Currently
Teaching
1.
Developmental Biology (BI 323)
2.
Animal Physiology (BI 229)
3.
Cell and Tissue Culture (BI 423)
4.
Lab. on Cell and Tissue Culture (BI 437)
5.
Elective: Animal Biotechnology (BI 427)
6.
Cell & Developmental Biology (BT 402)
7.
Elective: Animal Biotechnology (BT 433)
8.
Immunology (BI 326)
9.
Laboratory on Immunology (BI 334)
10.
Immunology (BT 411)
11.
Laboratory III- Immunology (BT 417)
Research Group
|
Ph.D
Students: |
Project
Student: |
||
|
Mr. Dipanjan Banerjee |
Ms. Saynaz Akhter Chowdhury Mail: saynaz29@gmail.com |
Ms. Sayani Mazumder Mail: mazumder.sayani17@gmail.com |
Ms. Archana Sinha |
M.Sc.
Student:
Ms. Lalita Chetry (Batch
2016-2018)
L a
b A l u m n i :
M.Sc. and
Int. M.Sc. Project Students
Ms. Triveni Borgohain (Batch
2012-2014)
Ms. Ankita Sarkar (Batch
2013-2015),
Ms. Anuradha Gautam (Batch
2013-2015)
Mr. Biplab Singha (M.Sc. Batch 2014-2016)
Ms. Sudeshna Saikia
(Int.
M.Sc. Batch 2011-2016)
Ms. Urbashi Neog (Int.
M.Sc. Batch 2011-2016)
Mr.
Somesh Roy (M.Sc. Batch 2015-2017)
Ms.
Tanusri Roy (M.Sc. Batch 2015-2017)
Ms. Manisha Paudyal (Int.
M.Sc. Batch 2012-2017)
Research Projects
|
Projects |
Amount |
Funding
source |
Period |
Status |
|
|
1. |
INSA Young Scientist Project |
Rs. 15.0 lakh |
Indian
National Science Academy, New Delhi, India. |
2014-2017 |
Completed |
|
2. |
UGC-Major Research Project |
Rs. 14. lakh |
University Grants
Commission, New Delhi, India. |
2015-2018 |
Ongoing |
|
3. |
DBT-IYBA Project |
Rs. 42.3 lakh |
Department of Biotechnology,
New Delhi, India. |
2015-2018 |
Ongoing |
|
4. |
SERB-Young Scientist Project |
Rs. 25.60 lakh |
Science and Engineering
Research Board, New Delhi, India. |
2015-2018 |
Ongoing |
|
5. |
DBT-Unit of Excellence
Project |
Rs. 116.70 lakh |
Department of Biotechnology,
New Delhi, India. |
2016-2019 |
Ongoing |
Research Publications:
Research
Articles:
(1)
S. Mukherjee, M. Chattopadhyay, S. Bhattacharya, S. Dasgupta, S. Hussain, S.K. Bharadwaj, D. Talukdar, A. Usmani,
B.S. Pradhan, S.S. Majumdar, P. Chattopadhyay, S. Mukhopadhyay, T.K. Maity, M.K.
Chaudhuri, S. Bhattacharya (2017) A small insulinomimetic molecule also
improves insulin sensitivity in diabetic mice. PLOS ONE 12(1): e0169809.
(2)
S. Agarwal, M. Chattopadhyay, S. Mukherjee, S. Dasgupta, S. Mukhopadhyay, S. Bhattacharya (2017) Fetuin-A
downregulates adiponectin through Wnt-PPARg
pathway in lipid induced inflamed
adipocyte. Biochim. Biophys. Acta. (Molecular Basis of
Disease) 1863(1): 174-181.
(3)
L. Goswami, S. Pratihar, S. Dasgupta,
P. Bhattacharyya, P. Mudoi, J. Bora, S.S. Bhattacharya, K.H. Kim (2016)
Exploring metal detoxification and accumulation potential during
vermicomposting of Tea factory coal ash: sequential extraction and fluorescence
probe analysis. Scientific Reports 6: e30402.
(4)
B. Gogoi, P. Chatterjee, S. Mukherjee, A.K. Buragohain, S. Bhattacharya, S. Dasgupta* (2014) A polyphenol
rescues lipid induced insulin resistance in skeletal muscle cells and
adipocytes. Biochem. Biophys. Res. Commun. 452(3): 382-8. *Corresponding
author.
(5)
T. Borgohain, B. Gogoi, A.K. Buragohain, S.
Dasgupta* (2014) Protective and curative effect of Scoparia dulcis leave extract against free fatty acid induced
insulin resistance in rat L6 myotubes. Am. J. Phytomed. Clin. Ther. 2(7):
842-854. *Corresponding author.
(6)
D. Pal#, S. Dasgupta#, R. Kundu, S.
Maitra, G. Das, S. Mukhopadhyay, S. Ray, S.S. Majumder, S. Bhattacharya (2012)
Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin
resistance. Nature Medicine 18(8): 1279-1285. #Contributed equally. [This article
was highlighted in Nature Medicine, Nature Chemical Biology, Nature Immunology, Cell, Diabetes and Science Signaling]
(7)
S. Seal, P. Chatterjee, S. Bhattacharya, D. Pal, S. Dasgupta, R. Kundu, S. Mukherjee, S. Bhattacharya, M. Bhuyan, P.
R. Bhattacharyya, G. Baishya, N.C. Barua, P. K. Baruah, P. G. Rao, S.
Bhattacharya (2012) Vapor of volatile oils from Litsea cubeba seed induces apoptosis and causes cell cycle arrest
in lung cancer cells. PLoS ONE 7(10): e47014.
(8)
R. Kundu#, S. Dasgupta#, A. Biswas,
S. Bhattacharya, B.C. Pal, S. Bhattacharya, P.G. Rao, N.C. Barua, M. Bordoloi,
S. Bhattacharya (2011) Carlinoside reduces hepatic bilirubin accumulation by
stimulating bilirubin-UGT activity through Nrf2 gene expression. Biochem.
Pharmacol. 82: 1186-1197. #Contributed equally.
(9)
S. Dasgupta, S. Bhattacharya, S.
Maitra, D. Pal, S.S. Majumdar, A. Datta, S. Bhattacharya (2011) Mechanism of
lipid induced insulin resistance: Activated PKCe is a key regulator. Biochim.
Biophys. Acta. (Molecular Basis of Disease) 1812: 495-506.
(10)
S. Dasgupta, S. Bhattacharya, A.
Biswas, S.S. Majumdar, S. Mukhopadhyay, S. Ray, S. Bhattacharya (2010) NF-kB
mediates lipid-induced fetuin-A expression in hepatocytes that impairs
adipocyte function effecting insulin resistance. Biochem. J. (Metabolism) 429:
451-462.
(11)
A. Biswas, S. Bhattacharya, S. Dasgupta,
R. Kundu, S.S. Roy, B.C. Pal, S. Bhattacharya (2010) Insulin resistance due to
lipid induced signaling defects could be prevented by mahanine. Mol.
Cell. Biochem. 336: 97-107.
(12)
P. Barma, S. Bhattacharya, A. Bhattacharya, R. Kundu, S. Dasgupta, A. Biswas, S. Bhattacharya, S.S. Roy, S. Bhattacharya
(2009) Lipid induced overexpression of NF-kB in skeletal
muscle cells is linked to insulin resistance. Biochim. Biophys. Acta.
(Molecular Basis of Disease) 1792: 190-200.
(13)
R. Kundu, S. Dasgupta, A. Biswas, A.
Bhattacharya, B.C. Pal, D. Bandyopadhyay, S. Bhattacharya, S. Bhattacharya
(2008). Cajanus cajan Linn.
(Leguminosae) prevents alcohol-induced rat liver damage and augments
cytoprotective function. J. Ethnopharmacol. 118: 440-447.
Review
Article:
S.
Bhattacharya, R. Kundu, S. Dasgupta,
S. Bhattacharya (2012) Mechanism of lipid induced insulin resistance: An
overview. Endocrinol. Metab. 27:12-19.
Book
Chapter:
S. Dasgupta, S.
Bhattacharya (2016) Lipid induced adipose tissue defects is associated with
insulin resistance and type 2 diabetes. "Recent Advances in Communicable and
Non-communicable Diseases" edited by Asis Datta and V.P. Sharma,
Capital Publish Co., page 406-415.
Patents filed:
(1)
M. Bhuyan, P. R. Bhattacharyya, P. K. Baruah, N. C. Barua, P.G. Rao, S.
Bhattacharya, R. Kundu, P. Chatterjee, S. Seal, S. Mukherjee, S. Dasgupta, S. Moitra, S.
Bhattacharya, S. Bhattacharya. A synergistic pharmaceutical composition useful
for the treatment of lung cancer. PCT International Application No.
PCT/IN2012/000581, International Filing Date: 05.09.2012. Publication No.
WO2014002104 A1, Publication Date: 03.01.2014.
(2)
M.K. Chaudhuri, S. Hussain, S. Bharadwaj, U.B. Sinha, D. Talukdar, A. Usmani,
S.S. Majumdar, S. Bhattacharya, S.
Dasgupta, R. Kundu, S. Bhattacharya, S. Bhattacharya; Insulin mimetic
active comprising oxodiperoxo vanadates and a pharmaceutical composition obtained
thereof. PCT International Application No. PCT/IN2011/000386, International
Filing Date: 09.06.2011. Publication No. WO/2012/131689, Publication Date:
04.10.2012.
(3)
S. Bhattacharya, S. Dasgupta, P.
Barma, A. Biswas, B.C. Pal, S. Bhattacharya, S. Bhattacharya, M. Bordoloi, N.C.
Barua, P.G. Rao; Method for inhibition of NF-kB gene expression. International Application No.:
PCT/IB2011/001580, International Filing Date: 07.07.2011. Publication No.
WO/2012/004653, Publication Date: 12.01.2012.
(4)
S. Bhattacharya, S. Dasgupta, S. Bhattacharya, S. Bhattacharya, M. Bordoloi, N. C.
Barua, P. G. Rao. 3,4-Dihydroxyallyl benzene and
2',3'-Epoxypropyl-3,4-dihydroxybenzebe demonstrated strong anti-cancer property
against cancer cells. International Application No.: PCT/IN2012/000212,
International Filing Date: 29.03.2012. Publication No. WO/2012/131717,
Publication Date: 04.10.2012.
(5)
A. Datta, S. Bhattacharya, B. C. Pal, J. Sen, S. Dasgupta, A. Biswas, J. Batra; Process for production of
anti-diabetic compound in root culture of Catharanthus roseus. International
Application No.: PCT/IN2011/000386, International Filing Date: 09.06.2011.
International Publication No. WO/2010/004584 Publication Date: 14.01.2010.
(6)
R. Kundu, S. Dasgupta, A. Biswas, B. C. Pal, S. Bhattacharya, S. Bhattacharya, N. C. Barua, P. G. Rao;
UDP-Glucuronosyl transferase (UGT) expression stimulant to reduce bilirubin
accumulation in liver and pharmaceutical compositions thereof. Patent Application
No. 0136DEL2010. Filing Date: 22.01.2010.
Membership in Academics bodies:
Life member – Society of
Biological Chemists (India)
Reviewer in International Journals:
(1)
Biochemical Journal (Portland Press) [IF: 3.797]
(2)
Journal of Physiology and Biochemistry (Springer) [IF: 2.444]
(3)
Journal of Functional Food (Elsevier) [IF: 3.144]
(4)
Bioscience Reports (Portland Press) [IF: 2.906]
(LAST UPDATED: FEBRUARY 15, 2018)