Molecular
Toxinology Laboratory Department of Molecular Biology and Biotechnology |
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Robin Doley, PhD Associate Professor
& Principal Investigator |
Research Interest:
Snake venom is a complex mixture of bioactive proteins and polypeptides produced and stored in the venom gland. They are responsible for the pharmacological manifestation in victims during envenomation by venomous snakes. Variation in the venom composition adds more to the complexities of pharmacological effects. Venom composition of single species varies due to age, sex, geographical locations and others. Due to this antivenoms available are ineffective in neutralizing all the toxic components of the venom. Therefore understanding the venom variation and bioactivity of these proteins and polypeptides is very important. This will help in designing strategies to overcome the limitations of antivenom therapy but also lead to drug discoveries. Therefore our research interest are 1) Understand variation of snake venoms proteins from different geographical locations, 2) Venomics and antivenomics of medically important snakes of India, 3) Understanding the structure-function relationship of these venom proteins for therapeutic applications.
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Research Projects
Research
Group
Lab Alumni
Publications
Google Scholar
Contact Address
Personal Details Principal Investigator Postdoc. (2005-2009): Protein Science Laboratory Dept. of Biological Sciences National University of Singapore, Singapore
PhD (2004): Dept. of Molecular Biology and Biotechnology Tezpur University, Assam, India
M.Sc. (1999): Dept. of Zoology Rajiv Gandhi University, Doimukh, Arunachal Pradesh, India
Position Held Associate Professor, Department of Molecular Biology and Biotechnology, Tezpur University, February 22, 2013 till date Assistant Professor, Department of Molecular Biology and Biotechnology, Tezpur University, October 2009 to February 22, 2013 Lecturer (Adhoc), Department of Molecular Biology and Biotechnology, Tezpur University, March 2009 to September 2009. Post Doctoral Fellow, National University of Singapore, March 2005 to March 2009 UGC Research Fellow, 2001 for pursuing doctoral research
Membership/Academic Distinctions / Honors / Awards Life member: Toxinological Society of India Life Member: Society of Biological Chemist (India) Member: International Society on Thrombosis and Haemostasis (ISTH) Member: International Society on Toxinology (IST) CSIR-SRF: 2003 Chancellor’s Gold Medal, Rajiv Gandhi University: 1999 Gold Medal in PG, Rajiv Gandhi University: 1999
Present and Past Administrative/Academic Assignments Member: Internal Quality Assurance Cell (IQAC) (2015-17) Reviewing Editor: Journal of Bioresource (ISSN 2394-4315) Member Secretary: Tezpur University Animal Ethical Committee (TUAEC) Member: Institutional Animal Ethical Committee (IAEC), DRL, Tezpur Member: Institutional Biosafety Committee (IBC), DRL, Tezpur Member: Institutional Biosafety Committee, Tezpur University Member: Sophisticated Instrument Facility, Tezpur University Member: Core Committee, Tezpur University Jonai Campus Associate editor, Newsletter, Toxinological Society of India, 2010 till 2014 Warden, New Women's Hostel, Tezpur University, August 2012 to July 2013 Warden, Brahmaputra Men's Hostel, Tezpur University, July 2010 to Aug 2012
Resource person 1. CEP on Ethanobotany and Folk Medicine: Exploration of Ethanomedicine of North-East India, DRL, Tezpur, December 12-16, 2011. 2. Biotech-Hub Workshop on Basic Genetic Engineering Techniques for Gene Cloning” Organized by Department of Molecular Biology and Biotechnology, Tezpur University. December 17-21, 2012. 3. Career Oriented Talk on Biotechnology, Darrang College, 17 Aug. 2013 4. Workshop on Molecular Structure Determination using X-ray Crystallography: Theory and Hands on Experience, Centre for Potential for Excellence in Biodiversity, Rajiv Gandhi University, 4-6 Sept. 2013 5. DBT sponsored workshop on "Techniques of Molecular Biology". Organized by Institutional Level Biotech Hub (IBT Hub), A. D. P College, Nagaon 752002, Assam. May 30-31, 2014 6. DBT sponsored workshop on "Biochemistry and Molecular Biology Techniques". Centre for Studies in Biotechnology Dibrugarh University, Dibrugarh, Assam. March 19-21, 2014 7. CEP course on "Advances in biotechnology and its impact on human health DRL, Tezpur, November 7-11, 2016.
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Simran Kaur DBT-JRF (2014), GATE (2013 & 14), SLET (2013) Ph. D Scholar (TZ121012) Email: simranATtezu.ernet.in Area of research: Cloning and expression of venom proteins
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Archana Deka DBT-JRF (2016), UGC-NET (2016), ICMR (2016) GATE (2015), SLET (2014) Ph. D Scholar (TZ110462) Email: archanadATtezu.ernet.in Area of research: Venomics and Antivenomics
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Rafika Yasmin UGC-NET (2016), UGC-JRF (2016), GATE
(2017), SLET (2018) Ph. D Scholar (TZ155926) Email: rafikayATtezu.ernet.in Area of research: Anti-platelet proteins from snake venom |
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Susmita Thakur GATE (2018), SLET (2018) Ph. D Scholar Email: susmitatATtezu.ernet.in Area of research: Venomics and Antivenomics |
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Arpita Devi UGC-NET (2015),
CSIR-JRF (2016 & 2017), GATE (2018) Ph. D Scholar Email:
darpitaATtezu.ernet.in Area of research: Design and development of
anti-thrombin peptides |
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Amit Talukdar CSIR NET JRF
(2017), SLET (2017) Ph.D Scholar Email: amit789ATtezu.ernet.in |
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PhD Students |
Title of the PhD Thesis |
Present Occupation |
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1. Dr. Diganta Das (2010-16) |
Studies on the crude venom and purified three-finger toxin of Naja kaouthia from North East India |
DBT-Post Doc Fellow @ IISc Bangalore |
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2. Dr. Maitreyee Sharma DST INSPIRE Fellow (2011-16) |
Proteomics of Indian Daboia russelii venom (Irula) and characterization of a major protein |
DBT-Post Doc Fellow @ CCMB Hyderabad |
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3. Dr. Rajeev Kungur Brahma DBT-SRF (2011-16) |
Identification and characterization of thrombin inhibitors from the salivary gland of tick (Haemaphysalis bispinosa) |
Research Associate @ DRL, Tezpur |
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Project Students |
Present Occupation |
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1. Rajeev K. Brahma (MSc 2010) |
Research Associate, DRL, Tezpur |
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2. Anoop S. Chauhan (MSc 2011) |
PhD, IMTECH Chandigarh |
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3. Shatabdi Bhattarcharjee (MSc 2011 |
PhD, Johns Hopkins Bloomberg School of
Public Health, USA |
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4. Vanlalrinchhani (MSc 2011) |
PhD, IISc Bangalore |
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5. Sharanya Chatterjee (MSc 2012) |
PhD, IISc Bangalore |
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6. Moushumee Das (MSc 2012) |
PhD, IIT Guwahati |
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7. Simran Kaur (MSc 2012) |
PhD, Tezpur
University |
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8. Raka Choudhury (MSc 2013) |
PhD, Wgeningen
University, Netherlands |
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9. Vishal Dixit (MSc 2013) |
PhD, Centre for Molecular Medicine,
University of Cologne, Germany |
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10. Aniket Girish Parab (MSc 2014) |
PhD, IISc Bangalore |
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11. Salik Miskat Borbora (MSc 2014) |
PhD, IISc Bangalore |
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12. Archana Deka (Int. MSc 2014) |
PhD, Tezpur University |
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13. Sharmistha Debnath (Int. MSc 2015) |
Biotech Job, Bangalore |
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14. Yash Verma (MSc 2015) |
PhD, Delhi University |
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15. Sumeet
Jhariya (MSc 2016) |
Bioentrepreneur |
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16. Rituparna Das (MSc 2016) |
PhD, BARC |
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17. Debarun Patra (MSc 2017) |
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18. Rafika Yasmin (MSc 2017) |
PhD, Tezpur
University |
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19. Mayashree
Das (Int. MSc 2017) |
PhD, IISc Bangalore |
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20. Jebin Ahmed (Int. MSc 2018) |
- |
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21. Sangeeta Paul (MSc 2018) |
PhD, IGIB, Delhi |
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22. Bhaskar Jyoti Saikia
(MSc 2018) |
Teaching Job |
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JRF/Project Fellows |
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1. Neeharika Gogoi 2. Debajit Kalita 3. Palakshi Das 5. Jotin Gogoi 6. Arpita Devi 7. Amit Talukdar |
PhD, NEHU, Shillong PhD, NEHU, Shillong PhD, CCMB, Hyderabad PhD, Tezpur University PhD, Tezpur University |
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Summer/Winter Trainees trained |
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Sl. No |
Name |
Year |
Institute |
1 2 3 4 5 6 7 8 9 10 11 12 13 |
Sumita Dutta Shama Hasrat Swagata Sharma Monoj Kr. Das Megha Lekharu Chayanika Sarmah Rimpi Saikia Sohini Chandrika Konwar Pinakshi Gohain Sheetal Ramani Taniya Talwar Pinku Mani Devi |
2010 2010 2010 2010 2011 2011 2012 2013 2014 2016 2016 2017 2017 |
Cotton College, Guwahati, Assam, India Jaipur National University, India SRM Institute of Science and Technology, Tamil Nadu, India Tezpur University, Tezpur Cotton College, Guwahati Cotton College, Guwahati Tezpur University, Tezpur Lovely Professional University, Jalandhar Daulat Ram College, University of Delhi SRM Institute of Science and Technology, Tamil Nadu, India Tezpur University, Tezpur Pragjyotish College, Guwahati Pragjyotish College, Guwahati |
14 |
Malaya Mili |
2018 |
Tezpur University, Tezpur |
15 |
Sagar Mazumdar |
2018 |
Tezpur University, Tezpur |
[Top] Associate Professor Department of Molecular Biology and Biotechnology Tezpur University Tezpur 784 028, Assam, India Contact: +91 3712 27 5412 Email: doley(AT)tezu.ernet.in; doleyr(AT)gmail.com Important Links PubMed | NCBI-BLAST | EBI | Protein Science Lab. NUS | TU Home |
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