First Phase Objectives
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a) Facilities for Kidney Transplant Patients:
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HLA typing for patients and donors -
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Protocols standardised by molecular method using invitrogen (ssp) kits. Patient service not yet provided.
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Cross match test for patients and donors prior to transplantation.
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Routinely done immediate pre-transplant test is done in the centre where transplantation is performed.
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Estimation of panel reactive antibodies of patients to assess the general immune response of individuals towards environmental antigens.
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Not done
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Monitoring of immune status of patient both in the pre transplant as well as in the posttransplant period.
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Not done
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If necessary assessment of immunostatus during an episode of rejection.
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Not done
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Estimation of antibody whether IgG/IgM/IgA -
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IgG and IgM done, IgA not done
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Estimation of autoantibodies
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Not done
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b) Facilities for other Patients:
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HLA Typing of Patients for the following Diseases:
i) Reiters disease
ii) Graves disease
iii) Rheumatoid Arthritis
iv) Juvenile Rheumatoid Arthritis
v) Insulin Dependent Diabetes Mellitus etc
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Not done.
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HLA Typing of relatives of patients who are at risk of developing the above mentioned diseases.
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Not done
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Testing for HLA B27 in patients Suspected to be suffering from Ankylosing Spondylitis
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Routinely done
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Second phase Objectives
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HLA typing of patients and Donors by both serology and molecular methods to identify an ABO compatible HLA identical donors from amongst the siblings of the patients
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Not done
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To perform HLA typing by molecular methods with DNA from the unborn sibling of a patient to ascertain whether the unborn offspring of the couple is normal and secondly to identify a potential donor for the patient.
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Not done
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Monitoring of the patient in the post transplant period as regard the acceptance or rejection of grafts.
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Not done
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